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View Data: Catalogue - Control View Data: Catalogue - Experimental View Data: Standardized Paper View Data: Experimental design and Complexity View Data: Experimental design and Complexity
View Data: Concentration Trap
This module provides access to tables of data that you can filter and sort. Since a considerable fraction of these data was published exclusively in graphs, these tables become a sole source for numerical data.
The screen can be sorted by all authors or first authors. Hierarchical data entry results in a well-defined collection of tables filled with standardized data. To view a given hierarchical level, click on its command button - it becomes highlighted in yellow. The point here is straightforward. If we want to have a data-driven biology, we have to have access to our data in digital form.
This screen duplicates for experimentals the presentation used for controls. Notice that data followed by a yes highlighted in red identify values significant differenent from their controls (P<0.05). The data of a given paper can be viewed as a standardized paper, wherein the organization is hierarchical. This screen includes control and experimental data pairs (proportions) fitted to decimal repertoire equations (DREs). These data and equations become the raw materials for creating new forms of information. This scrolling table offers both local and global views of the way biology connects its parts. It shows us what biology can do with the information stored in its genome.
Know the proportions of the parts and express them as equations, and you can reverse and forward engineer biology. This exercise uses published data to forward-engineer several parts of the hippocampus in humans, monkeys, rats, mice, and shrews. Enter a seed value; press Enter, and presto a new hippocampus. This module, available only on the software tree, is included here to highlight the relationship of complexity to experimental design and analysis. By running simulations with these screens, you will quickly understand the limits of reductionism when applied to the complex settings of biology.
This screen, available only on the software tree, explores the relationship of concentrations to absolute amounts when looking for biological changes. The document offers additional information.
This module provides access to tables of data that you can filter and sort. Since a considerable fraction of these data was published exclusively in graphs, these tables become a sole source for numerical data.
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